Review
Nature Reviews Neuroscience 4, 496-505 (June 2003) | doi:10.1038/nrn1113
Reelin and brain development
Fadel Tissir1 & André M. Goffinet1 About the authors
Abstract
Over the last 50 years, the reeler mutant mouse has become an important model for studying normal and abnormal development in the cerebral cortex and other regions of the brain. However, we are only just beginning to understand the actions of reelin — the protein that is affected by the reeler mutation — at the molecular and cellular level. This review discusses the most recent advances in this research field, and considers the merits of the various models that have been put forward to explain how reelin works.
- View At a Glance
Author affiliations
- Developmental Genetics Unit, Université Catholique de Louvain, UCL 7382, 73 Avenue E. Mounier, B1200 Brussels, Belgium.
Correspondence to: André M. Goffinet1 Email: Andre.Goffinet@gede.ucl.ac.be
|
MORE ARTICLES LIKE THIS These links to content published by NPG are automatically generated REFERENCE NEWS AND VIEWS RESEARCH |
is essential for hippocampal neuronal migration and long-term potentiation
