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LTP: perils and progress

Nature Reviews Neuroscience volume 4, pages 926–929 (2003)Cite this article

Abstract

On the thirtieth birthday of long-term potentiation (LTP), it is appropriate to step back from the fray, evaluate what has been learned and look to the future. Two of us (J.W.L. and J.R.S.) published such an evaluation a few years ago in the hope that the ignorance conferred to us by our status as outsiders to the field might be offset, at least in part, by a freshness of perspective. The responses to that article have been numerous and fascinating, with experts and non-experts raising points in private that would benefit from open discussion. Here, joined by an LTP 'insider' (J.L.), we initiate such a discussion, restating, clarifying and debating some of the points that were raised in the original article.

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Author information

Authors and Affiliations

  1. the Department of Biology, Brandeis University, Waltham, 02454, Massachusetts, USA

    John Lisman

  2. the Department of Anatomy and Neurobiology, Washington University School of Medicine, 660 South Euclid, Campus Box 8108, St Louis, 63110-1093, Missouri, USA

    Jeff W. Lichtman & Joshua R. Sanes

Authors
  1. John Lisman
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  2. Jeff W. Lichtman
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  3. Joshua R. Sanes
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Correspondence to John Lisman.

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Lisman, J., Lichtman, J. & Sanes, J. LTP: perils and progress. Nat Rev Neurosci 4, 926–929 (2003). https://doi.org/10.1038/nrn1259

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