Perspectives

Nature Reviews Neuroscience 3, 655-666 (August 2002) | doi:10.1038/nrn894

OpinionHow do you feel? Interoception: the sense of the physiological condition of the body

A. D. Craig1  About the author

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As humans, we perceive feelings from our bodies that relate our state of well-being, our energy and stress levels, our mood and disposition. How do we have these feelings? What neural processes do they represent? Recent functional anatomical work has detailed an afferent neural system in primates and in humans that represents all aspects of the physiological condition of the physical body. This system constitutes a representation of 'the material me', and might provide a foundation for subjective feelings, emotion and self-awareness.

Author affiliations

  1. A. D. (Bud) Craig is at the Atkinson Pain Research Laboratory, Division of Neurosurgery, Barrow Neurological Institute, Phoenix, Arizona 85013, USA.
    Email: bcraig@chw.edu
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