Figure 2 | Pathways in neurons, astrocytes and microglia that are implicated in -amyloid toxicity.   The figure serves to illustrate the idea that many cellular elements are involved in more than one function or pathway, and are dynamic in that their use in one direction might have an impact on other functions. The development of models of this type, with an ever-increasing degree of sophistication, will foster our understanding of brain function as a dynamic process. See Ref. 9 for details of the elements included in this model of -amyloid toxicity. Reproduced with permission from Ref. 8 © 2001 Macmillan Magazines Ltd.

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© 2002 Nature Publishing Group