Review
Nature Reviews Neuroscience 3, 943-951 (December 2002) | doi:10.1038/nrn989
Parsing the prosencephalon
Murielle Rallu1, Joshua G. Corbin1 & Gord Fishell1 About the authors
Abstract
The forebrain, or prosencephalon, consists of the diencephalon and the telencephalon. The diencephalon is the conduit for ascending sensory information, whereas the telencephalon is the highest-order processor of neural function, and is consequently the most complex region of the nervous system. In this review, we discuss how fate restrictions, starting from the induction of neural character, result in the sequential specification of anterior neural tissue, forebrain and telencephalon, and finally dorsoventral patterning. Rather than relying on novel signalling pathways, the complexity of the mature brain seems to result from the unique ordering of signals used widely during development.
- View At a Glance
Author affiliations
- Developmental Genetics Program and the Department of Cell Biology, The Skirball Institute of Biomolecular Medicine, New York University Medical Center, 540 First Avenue, New York, New York 10016, USA.
Correspondence to: Gord Fishell1 Email: fishell@saturn.med.nyu.edu
|
MORE ARTICLES LIKE THIS These links to content published by NPG are automatically generated REFERENCE NEWS AND VIEWS RESEARCH |
