Review
Nature Reviews Neuroscience 3, 803-812 (October 2002) | doi:10.1038/nrn941
Activity-dependent regulation of dendritic growth and patterning
Rachel O. L. Wong1 & Anirvan Ghosh2 About the authors
Abstract
One of the most remarkable features of the developing brain is its ability to undergo structural change in response to experience. Among the cellular elements that show this kind of plasticity are dendrites, which are the components that receive and process synaptic information. Recent observations indicate that calcium signalling in neurons can regulate dendritic growth and remodelling by several mechanisms, and these mechanisms are likely to be key mediators of structural plasticity in the developing brain.
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Author affiliations
- Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
- Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
Correspondence to: Anirvan Ghosh2 Email: aghosh@jhmi.edu
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