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The emotional valence of a memory can be changed, and this probably involves a change in the connectivity between hippocampal and amygdalar memory traces.
Dynamic regulation of ion concentrations across the cellular membrane is vital for neuronal function. In this article, Kaila and colleagues review the contribution of members of the cation-chloride cotransporters to neuronal signalling, connectivity, plasticity and disease.
It is commonly thought that the dorsal hippocampus is implicated in memory and spatial navigation and the ventral hippocampus in anxiety-related behaviours. On the basis of gene expression, anatomical and electrophysiology studies, Strange and colleagues propose a new model of hippocampal functional anatomy, in which functional long-axis gradients are superimposed on discrete functional domains.
Social prejudices and stereotyping are pervasive and often operate unconsciously. In this Review, David M. Amodio considers the neural basis of prejudice and stereotyping and discusses the processes through which such biases may form, can influence behaviour and are regulated.
The application of network science to several common neurological disorders challenges the idea that these disorders are either 'local' or 'global'. In this Review, Kees Stam proposes a model of hub overload and failure as a possible final common pathway in diverse neurological disorders.