Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
An international collaboration has mapped the transcriptome of the adult human brain in unprecedented detail, sampling around 900 defined anatomical sites and providing a wealth of freely available data.
Gamma activity in neuron groups in visual area V4 synchronizes selectively with gamma activity in those neuron groups in primary visual cortex that provide behaviourally relevant input.
Social isolation during a critical post-weaning period reduces myelination in the prefrontal cortex (PFC) by altering oligodendrocyte neuregulin 1–receptor tyrosine kinase ERBB3 signalling and impairs PFC function.
The mechanisms underlying hearing loss following traumatic noise exposure are not well understood. In this study, Chenet al. show that the cellular energy depletion that occurs following traumatic noise exposure results in activation of small GTPases and downstream effectors that mediate apoptotic and necrotic cell death.
The transition in worker bees between nursing and foraging subcastes is shown to be associated with reversible changes in gene methylation in the honeybee brain.
Chronic stress causes a switch in the actions of corticotropin-releasing factor in the nucleus accumbens, from promoting dopamine release and inducing an appetitive state to inducing an aversive state.
Aberrant matrix metalloproteinase (MMP) activity is a well-known contributor to synaptic dysfunction and neuronal loss in CNS injury and disease. In this Review, George W. Huntley discusses how MMPs also make an important contribution to synaptic functional and structural remodelling under nonpathophysiological conditions.
Honeybees exhibit complex social, navigational and communication behaviours, controlled by a nervous system of around 1 million neurons. In this Review, Randolf Menzel discusses the utility of the honeybee as a model organism for the study of a wide range of important cognitive functions, including learning and memory.
Post-traumatic stress disorder is associated with changes in psychophysiological, neuroimaging, endocrinological and genetic measures. Animal studies have begun to elucidate its neurobiological mechanisms. Pitman and colleagues review these findings and discuss directions for research aimed at identifying risk factors, biomarkers and preventive and therapeutic interventions.
Since its emergence, the field of neuroeconomics has gained much attention but has also been subject to criticism. In this Perspective, the authors analyse the neuroeconomics literature and the social networks within the neuroeconomics community and consider whether the field represents a truly integrated discipline.
The BCM theory of synaptic plasticity is now 30 years old. In this Perspective article, Cooper and Bear discuss how this theory has advanced our understanding of synaptic plasticity, learning and memory and highlight the important role that theory can have in neuroscience research.
