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Research Highlights
Nature Reviews Neuroscience 10, 546 (1 August 2009) | doi:10.1038/nrn2684
Neuronal plasticity: Mossy fibres WNT more contact with CA3
Abstract
Living in a stimulating environment has cognitive benefits for humans and animals alike, and hippocampal neurons in particular show structural plasticity in response to environmental manipulations. Gogolla et al. now show that environmental enrichment produces a net global increase in synapse densities in the hippocampus, which at mossy-fibre–CA3 synapses depends on WNT signalling.
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