Review
Nature Reviews Neuroscience 10, 319-332 (May 2009) | doi:10.1038/nrn2631
Microtubule assembly, organization and dynamics in axons and dendrites
Cecilia Conde1 & Alfredo Cáceres1 About the authors
Abstract
During the past decade enormous advances have been made in our understanding of the basic molecular machinery that is involved in the development of neuronal polarity. Far from being mere structural elements, microtubules are emerging as key determinants of neuronal polarity. Here we review the current understanding of the regulation of microtubule assembly, organization and dynamics in axons and dendrites. These studies provide new insight into microtubules' function in neuronal development and their potential contribution to plasticity.
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Author affiliations
- Laboratorio de Neurobiología Celular y Molecular, Instituto Investigación Médica Mercedes y Martín Ferreyra (INIMEC-CONICET), Friuli 2434, 5016 Córdoba, Argentina.
Correspondence to: Alfredo Cáceres1 Email: acaceres@immf.uncor.edu
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