Current Issue
From the editors
p761 | doi:10.1038/nrn2750
Research Highlights
Psychiatric disorders: DISC1 drives development through girdin | PDF (149 KB)
p763 | doi:10.1038/nrn2746
Neurodegenerative disease: Sleeping away amyloid plaques? | PDF (136 KB)
p764 | doi:10.1038/nrn2742
In brief
Neurodegenerative disease | Visual system | Ion channels | Therapeutic strategies | PDF (116 KB)
p764 | doi:10.1038/nrn2751
Neurological disorders: Connectivity in Rett | PDF (213 KB)
p765 | doi:10.1038/nrn2744
Affective disorders: Antidepressant action through gene regulation | PDF (183 KB)
p765 | doi:10.1038/nrn2749
Neuroimaging: Learning changes the resting brain | PDF (156 KB)
p766 | doi:10.1038/nrn2743
Synaptic plasticity: Astrocytes as regulators | PDF (135 KB)
p766 | doi:10.1038/nrn2745
Development: Scaling with microRNAs | PDF (194 KB)
p766 | doi:10.1038/nrn2747
In brief
Oscillations | Reward | Pain | Spatial awareness | PDF (103 KB)
p767 | doi:10.1038/nrn2752
Reviews
Modes and regulation of glial migration in vertebrates and invertebrates
Christian Klämbt
p769 | doi:10.1038/nrn2720
To reach their final destinations within the nervous system, glial cells must often migrate over long distances. Klämbt discusses the mechanisms of glial cell migration, highlighting common mechanisms and differences between vertebrate and invertebrate glial migration.
Zinc in the physiology and pathology of the CNS
Stefano L. Sensi, Pierre Paoletti, Ashley I. Bush & Israel Sekler
p780 | doi:10.1038/nrn2734
An important role for zinc homeostasis in brain function has recently emerged. Sensi and colleagues review the evidence pointing to the physiological role of zinc in the regulation of synaptic excitability and to its pathophysiological role in brain trauma and Alzheimer's disease.
What does the retrosplenial cortex do?
Seralynne D. Vann, John P. Aggleton & Eleanor A. Maguire
p792 | doi:10.1038/nrn2733
Vann and colleagues review anatomical, lesion and imaging studies suggesting that the retrosplenial cortex is involved in navigation and memory. They propose that it achieves this function through a key role in scene construction by translating between different perspectives of the environment.
Article series: Sleep
REM sleep and dreaming: towards a theory of protoconsciousness
J. Allan Hobson
p803 | doi:10.1038/nrn2716
Brain activation during REM sleep and dreaming resembles that during waking, but what is the meaning of this activity? Allan Hobson discusses the emergence of REM sleep states during evolution and development and proposes that the activity constitutes a protoconscious state.
Perspectives
Science and society
Neuroculture
Giovanni Frazzetto & Suzanne Anker
p815 | doi:10.1038/nrn2736
Advances in brain research capture public attention not only through the media but also through the arts and commercial products. Frazzetto and Anker reflect on the numerous cultural products that are inspired by neuroscience research and highlight the dialogue between science and culture.
Innovation
The Allen Brain Atlas: 5 years and beyond
Allan R. Jones, Caroline C. Overly & Susan M. Sunkin
p821 | doi:10.1038/nrn2722
Five years after the launch of the Allen Brain Atlas, Jones and colleagues describe the challenges faced during the early years of the project, the contributions that it has made to neuroscience research to date and the opportunities for its use in the future.
Correspondence
Correspondence: The functional anatomy of the frontal lobes
Parashkev Nachev, Christopher Kennard & Masud Husain
p829 | doi:10.1038/nrn2667-c1
Corrigendum: The origin and evolution of synapses
Tomás J. Ryan & Seth G. N. Grant
p829 | doi:10.1038/nrn2748
