Perspectives

Nature Reviews Neuroscience 10, 59-70 (January 2009) | doi:10.1038/nrn2555

OpinionHow do you feel — now? The anterior insula and human awareness

A. D. (Bud) Craig1  About the author

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The anterior insular cortex (AIC) is implicated in a wide range of conditions and behaviours, from bowel distension and orgasm, to cigarette craving and maternal love, to decision making and sudden insight. Its function in the re-representation of interoception offers one possible basis for its involvement in all subjective feelings. New findings suggest a fundamental role for the AIC (and the von Economo neurons it contains) in awareness, and thus it needs to be considered as a potential neural correlate of consciousness.

Author affiliations

  1. A. D. (Bud) Craig is at the Atkinson Research Laboratory, Barrow Neurological Institute, Phoenix, Arizona 85013, USA.
    Email: bcraig@chw.edu

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