Nature Reviews Neuroscience
Volume 10, No 11 November 2009
Featured Article
Zinc in the physiology and pathology of the CNS
Stefano L. Sensi, Pierre Paoletti, Ashley I. Bush & Israel Sekler
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Advance online publication
Review
Plasticity during stroke recovery: from synapse to behaviour
Timothy H. Murphy & Dale Corbett
Evidence suggests that a time–limited window of plasticity exists following a stroke, during which most behavioural recovery occurs. Murphy and Corbett describe advances in our understanding of plasticity and recovery after stroke and highlight parallels with developmental plasticity.
Advance online publication
Review
microRNAs at the synapse
Gerhard Schratt
MicroRNAs are emerging as key modulators of post-transcriptional gene regulation in the synaptodendritic compartment. Here, Schratt reviews recent studies showing that neural activity controls microRNA transcription, subcellular localization, processing and function, and discusses the relevance of microRNAs for synapse development and plasticity.
Current Issue
Science and society
Neuroculture
Giovanni Frazzetto & Suzanne Anker
Advances in brain research capture not only public attention through the media but also through the arts and commercial products. Frazzetto and Anker reflect on the numerous cultural products that are inspired by neuroscience research and highlight the dialogue between science and culture.
Current Issue
Perspective
The Allen Brain Atlas: 5 years and beyond
Allan R. Jones, Caroline C. Overly & Susan M. Sunkin
Five years after the launch of the Allen Brain Atlas, Jones and colleagues describe the challenges faced during the early years of the project, the contributions that it has made to neuroscience research to date and the opportunities for its use in the future.
Current Issue
Research Highlights
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Psychiatric disorders:
DISC1 drives development through girdin
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Synaptic plasticity:
Astrocytes as regulators
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Development:
Scaling with microRNAs
Focus issue
CNS evolution
This focus issue — sponsored by the Wellcome Trust — celebrates the contribution of Darwin's ideas to our current understanding of the evolution of the nervous system. It includes articles that discuss the molecular, cellular and structural changes that have contributed to CNS evolution, and their functional consequences.
Gain free access to this issue until 31st March 2010 here
More Neuroscience
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Recommended Links
Links recommended by the editors
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Neuropod
Neuroscience podcast from Nature
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Web Focus Collection
Selected articles from the Nature Publishing Group
Noticeboard
Focus on Neuroimmunology
Understanding the crosstalk between the nervous and immune systems and how it can be dysregulated provides us with crucial insights necessary for the treatment of neurological diseases such as multiple sclerosis and Alzheimer's disease. Nature Reviews Immunology presents a special Focus issue featuring articles that review our current understanding of the immunopathogenesis of and emergent immunotherapies for these neurological diseases.
Focus on Stress
The body's response to stress has adaptive value, but exposure to chronic or severe stress — which is not uncommon in humans — can have long–lasting effects on brain structure and function, which can lead to changes in cognition and to disorders such as depression and post–traumatic stress disorder. This Focus issue highlights recent developments in this field, with a view to understanding the mechanisms that trigger and mediate stress responses, which will enable the development of therapeutic strategies aimed at treating stress–related disorders.
CNS precursors series
A series of articles highlighting recent advances in the identification of precursor cells and in our understanding of their regulation and functional roles.
Sleep series
A series of articles highlighting the genetic, cellular and systems basis of sleep and the importance of sleep for cognitive function and mental health.
Neuron–glia interactions series
A series of articles highlighting the interactions between different types of glia and neurons at the cellular and network levels.
Memory systems series
A special series of articles highlighting different types of memory and how they are represented in the brain.
Signalling in development series
A special series of articles highlighting recent progress in our understanding of the molecular mechanisms that are involved in all aspects of neural development.
Neuroimaging series
A special series of articles highlighting applications of neuroimaging techniques in all areas of neuroscience, including basic neurobiology, cognitive and behavioural neuroscience, translational neurology and clinical practice.
2008 Journal Citation Report (Thomson Reuters, 2009)
