Supplement

Evaluating diagnostics: The CD4 guide

November

Accurate CD4 counts are crucial laboratory markers for assessing immunodeficiency and the risk of disease progression in HIV-1 infection. HIV-1 causes a huge burden of morbidity and mortality, particularly in developing countries. This fourth supplement in the series focuses on CD4 immunodiagnostics, which can be used to monitor CD4 counts, and decide when to treat individuals with antivirals and whether treatments are effective.

November Vol. 6, Issue 11s

Supplement

Evaluating Diagnostics: The VL Guide

November

This third supplement in the series focuses on visceral leishmaniasis, which causes more than 50,000 deaths annually, a death toll that is surpassed among the parasitic diseases only by malaria.

This supplement is part of the Global Theme Issue on Poverty and Human Development, organized by the Council of Science Editors. All articles from Nature Publishing Group are available free at www.nature.com/povhumdev. The content from all participating journals can be found at www.councilscienceeditors.org/globalthemeissue.cfm

November Vol. 5, Issue 11s

Supplement

Evaluating Diagnostics: The STI Guide

December

This second supplement in the series focuses on the bacterial sexually transmitted infections syphilis, chlamydia and gonorrhoea, which cause a huge burden of morbidity and mortality, particularly in women in developing countries.

December Vol. 4, Issue 12s

Supplement

Evaluating Diagnostics: The Malaria Guide

September

Effective, quality-assured diagnostics have a crucial role in successful patient management and infectious disease control. This supplement is the first in a series of user-friendly operational guides explaining how to conduct evaluations of diagnostic tests for infectious diseases that are of public health importance in the developing world. The first in the series is the malaria guide.

September Vol. 4, Issue 9s