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Editorial

Nature Reviews Microbiology 7, 90 (1 February 2009) | doi:10.1038/nrmicro2086

If you build it, they might come

Roy Welch & Laura Welch

To annotate an organism's genome, biological information about the organism must be matched to the genes and genetic elements in the sequenced genome. The process is iterative and open-ended: new information is constantly incorporated into the annotation.