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Nature Reviews Microbiology 6, 497 (1 July 2008) | doi:10.1038/nrmicro1943

Bacterial secretion: Structural snapshot

Sheilagh Molloy

The chaperone–usher (CU) pathway is responsible for the secretion of cell-surface structures in Gram-negative bacteria, including the type 1 and P pili in pathogenic Escherichia coli. In a recent issue of Cell, researchers from the laboratories of Scott Hultgren, David Thanassi, Gabriel Waksman and Huilin Li provide a snapshot of the CU translocation machinery in action.