Review

Nature Reviews Microbiology 6, 741-751 (October 2008) | doi:10.1038/nrmicro1969

Focus on: Symbiosis

Wolbachia: master manipulators of invertebrate biology

John H. Werren1, Laura Baldo2 & Michael E. Clark1  About the authors

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Wolbachia are common intracellular bacteria that are found in arthropods and nematodes. These alphaproteobacteria endosymbionts are transmitted vertically through host eggs and alter host biology in diverse ways, including the induction of reproductive manipulations, such as feminization, parthenogenesis, male killing and sperm–egg incompatibility. They can also move horizontally across species boundaries, resulting in a widespread and global distribution in diverse invertebrate hosts. Here, we review the basic biology of Wolbachia, with emphasis on recent advances in our understanding of these fascinating endosymbionts.

Author affiliations

  1. Biology Department, University of Rochester, Rochester, New York, New York 14627, USA.
  2. Biology Department, University of California, Riverside, California 92521, USA.

Correspondence to: John H. Werren1 Email: werr@mail.rochester.edu

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