TABLE 1 | A 2×2 table to evaluate test performance

From the following article:

Evaluation of diagnostic tests for infectious diseases: general principles

Shabir Banoo, David Bell, Patrick Bossuyt, Alan Herring, David Mabey, Freddie Poole, Peter G Smith, N. Sriram, Chansuda Wongsrichanalai, Ralf Linke, Rick O'Brien, Mark Perkins, Jane Cunningham, Precious Matsoso, Carl Michael Nathanson, Piero Olliaro, Rosanna W. Peeling & Andy Ramsay

Nature Reviews Microbiology 5, S21-S31 (November 2007)

doi:10.1038/nrmicro1523

Test under evaluationReference standard testTotal
 PositiveNegative 
Positiveaba + b
Negativecdc + d
Totala + cb + d 
Test sensitivity = a/(a + c); test specificity = d/(b + d); PPV = a/(a + b); NPV = d/(c + d).
a = true positive, b = false positive; c = false negative; d = true negative

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