Abstract

The opportunistic intracellular pathogen Listeria monocytogenes has become a paradigm for the study of host–pathogen interactions and bacterial adaptation to mammalian hosts. Analysis of L. monocytogenes infection has provided considerable insight into how bacteria invade cells, move intracellularly, and disseminate in tissues, as well as tools to address fundamental processes in cell biology. Moreover, the vast amount of knowledge that has been gathered through in-depth comparative genomic analyses and in vivo studies makes L. monocytogenes one of the most well-studied bacterial pathogens.

Author affiliations

1. Institut Pasteur, Unité des interactions Bactéries cellules, Paris 75015, France.
2. Institut National de la Santé et de la Recherche Médicale, U604, Paris 75015, France.
3. Institut National de la Recherche Agronomique, USC2020, Paris 75015, France.

Correspondence to: Pascale Cossart^1,2,3 Email: pcossart@pasteur.fr

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