Table of contents
November 2006 Vol 4 No 11
In this issue
p799 | doi:10.1038/nrmicro1548
Editorial: Microorganisms and clean energy
p800 | doi:10.1038/nrmicro1534
Research Highlights
Toxins: SubAB — a specifically deadly toxin
p801 | doi:10.1038/nrmicro1542
HIV: Relief for tired T cells
p802 | doi:10.1038/nrmicro1533
Bacterial physiology: Sweet deception
p802 | doi:10.1038/nrmicro1545
Bacterial genetics: Deinococcus does the two-step
p803 | doi:10.1038/nrmicro1540
Plant disease resistance: An open and shut case
p804 | doi:10.1038/nrmicro1543
Bacterial physiology: Pinpointing the pathway
p804 | doi:10.1038/nrmicro1544
Viruses and Cancer: Viral hijacking
p804 | doi:10.1038/nrmicro1546
In brief
Symbiosis | Bacterial pathogenicity | Quorum sensing
p805 | doi:10.1038/nrmicro1547
News and Analysis
Genome watch
The grapes of wrath
p806 | doi:10.1038/nrmicro1535
Disease watch
Antibiotics stashed in UK homes | Cheap antibiotic boon for lymphatic filariasis? | Centralized food distribution and pathogen spread | WHO backs use of DDT | Phage spray spells death for | Frustration of untested AIDS vaccines | Battling staphylococcal infection | Smart wipe detects pathogens | UNITAID for drugs | Cholera epidemic crisis in Angola | Outbreak news
p808 | doi:10.1038/nrmicro1536
Reviews
The type III secretion injectisome
Guy R. Cornelis
p811 | doi:10.1038/nrmicro1526
The type III secretion injectisome delivers bacterial proteins into the cytosol of eukaryotic target cells. Here, Guy Cornelis reviews our current understanding of the structure, assembly and operation of this nanomachine.
Bacterial populations as perfect gases: genomic integrity and diversification tensions in Helicobacter pylori
Josephine Kang and Martin J. Blaser
p826 | doi:10.1038/nrmicro1528
The article focuses on the tensions between the opposing forces of maintaining genome integrity and increasing genome diversification in Helicobacter pylori. The authors propose that this generates a dynamic pool of genetic variants that is sufficiently diverse to occupy the different niches in the stomach.
Viruses of the Archaea: a unifying view
David Prangishvili, Patrick Forterre and Roger A. Garrett
p837 | doi:10.1038/nrmicro1527
Cultured archaeal viruses, which so far all have double-stranded DNA genomes, come in all shapes and sizes, with the range of virion morphotypes surpassing that found in the viruses of the Bacteria. The authors present a unifying view of this fascinating viral group.
The silent path to thousands of merozoites: the Plasmodium liver stage
Miguel Prudêncio, Ana Rodriguez and Maria M. Mota
p849 | doi:10.1038/nrmicro1529
The liver stage of Plasmodium infection constitutes an appealing target for the development of vaccines or prophylatic drugs as this step in the life cycle is obligatory but occurs before the onset of pathology. This Review summarizes the current knowledge on this stage of the Plasmodium life cycle.
Perspectives
Innovation
Glycan microarray technologies: tools to survey host specificity of influenza viruses
James Stevens, Ola Blixt, James C. Paulson and Ian A. Wilson
p857 | doi:10.1038/nrmicro1530
The global spread of H5N1 avian influenza virus has raised concerns that H5N1 might adapt to the human host and cause the next human influenza pandemic. Novel glycan array technologies can rapidly assess the receptor specificity of influenza viruses, detecting changes that might signal human adaptation.
Opinion
Genomics meets HIV-1
Amalio Telenti and David B. Goldstein
p865 | doi:10.1038/nrmicro1532
Humans vary in their susceptibility to HIV infection, and identifying the host genetic factors that cause this variation is a priority for vaccine development. Progress in high-throughput genotyping and in knowledge about human genetic variation allows systematic searching for genetic variants that influence the human response to HIV-1.
Corrigendum: Methods for predicting bacterial protein subcellular localization
Jennifer L. Gardy and Fiona S. L. Brinkman
| doi:10.1038/nrmicro1539
