|
Nature Reviews Microbiology
3,
893-899
(2005);
doi:10.1038/nrmicro1267
ANTIBODY-BASED THERAPIES FOR MALARIA
Richard J. Pleass & Anthony A. Holder
about the authors
Abstract
Antibodies are multifunctional glycoproteins that are found in blood and tissue fluids, and can protect against malaria by binding and neutralizing malaria parasites and preparing them for destruction by immune cells. Important technical advances mean that it is now possible to synthesize antibodies against important Plasmodium antigens that could be used for therapeutic purposes. These reagents could be designed to act like a drug and kill parasites directly, or could be used in vaccine strategies to protect individuals from infection. In this article, we discuss the possible therapeutic uses of antibodies in the treatment and prevention of malaria.
To benefit from the full content of Nature Reviews Microbiology every month, simply take out a subscription -
click here
for details.
|
