Review
Nature Reviews Microbiology 3, 59-69 (January 2005) | doi:10.1038/nrmicro1066
Viral modulation of NK cell immunity
Melissa B. Lodoen1 & Lewis L. Lanier1 About the authors
Abstract
Natural killer (NK) cells have been implicated in innate immune responses against viruses such as herpesviruses, which cause persistent infections in the host. In response to the selective pressure that is exerted by NK cells, many viruses have evolved strategies either to evade detection by NK cells or to modulate the activity of NK cells. Here, we review the unique relationship that exists between NK cells and viruses, with a focus on herpesviruses.
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Author affiliations
- Department of Microbiology and Immunology and the Cancer Research Institute, University of California San Francisco, 513 Parnassus Avenue, HSE 1001G, Box 0414, San Francisco, California 94143-0414, USA.
Correspondence to: Lewis L. Lanier1 Email: lanier@itsa.ucsf.edu
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