FIGURE 5 | Viral cytokines and chemokines encoded by EBV, KSHV and HVS.

From the following article:

Oncogenic gamma-herpesviruses: comparison of viral proteins involved in tumorigenesis

Blossom Damania

Nature Reviews Microbiology 2, 656-668 (August 2004)

doi:10.1038/nrmicro958

Oncogenic |[gamma]|-herpesviruses: comparison of viral proteins involved in tumorigenesis

a | The EBV vIL-10 cytokine can support B-cell proliferation and inhibit MHC class I antigen presentation. b | The KSHV vIL-6 cytokine promotes B-cell proliferation by directly interacting with gp130 and the KSHV vCCLs seem to direct inflammatory cell recruitment towards a TH2-type response. c | The HVS vIL-17 cytokine can promote T-cell proliferation. EBV, Epstein–Barr virus; KSHV, Kaposi's sarcoma-associated herpesvirus; HVS, herpesvirus saimiri; IL, interleukin; MHC, major histocompatibility complex.

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