Review
Nature Reviews Microbiology 2, 898-907 (November 2004) | doi:10.1038/nrmicro1021
Escherichia coli acid resistance: tales of an amateur acidophile
John W. Foster1 About the author
Abstract
Gastrointestinal pathogens are faced with an extremely acidic environment. Within moments, a pathogen such as Escherichia coli O157:H7 can move from the nurturing pH 7 environment of a hamburger to the harsh pH 2 milieu of the stomach. Surprisingly, certain microorganisms that grow at neutral pH have elegantly regulated systems that enable survival during excursions into acidic environments. The best-characterized acid-resistance system is found in E. coli.
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Author affiliations
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Department of Microbiology and Immunology, University of South Alabama College of Medicine, Mobile, Alabama 36695, USA.
Email: fosterj@sungcg.usouthal.edu
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