Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
This study identifies a non-genetic colistin-resistant subpopulation that is distinct from persisters as it causes acute infection and lethality during the course of treatment with antibiotics.
Adipose tissue is a novel niche forT. bruceiin mammalian hosts, and the parasite may adapt its metabolism in this niche to use fatty acids as a carbon source.
This study shows that Qsp1 is an autoregulatory signalling peptide that matures extracellularly and is imported into the cell by Opt1 to regulate virulence. This is the first description of the molecular mechanisms that are involved in eukaryotic quorum sensing.
Super-resolution microscopy shows that the localization of each mRNA inEscherichia coliis determined by whether the mRNA encodes an inner-membrane protein.
Many host structures are vital for viral infection and the endoplasmic reticulum (ER), in particular, is essential. In this Review, Tsai and colleagues highlight examples of subversion of the ER by diverse viruses to promote all stages of their life cycle, from entry to egress.
In the modern world, several factors have increased the global health challenge posed by noroviruses. In this Review, Koopmans and colleagues describe advances in the study of norovirus transmission, pathogenesis and evolution, and consider future prospects for therapeutics.
Molecular-based studies of fungal biodiversity have revealed fundamental differences from the biodiversity of bacteria, plants and animals. In this Review, Peay and colleagues consider the roles of ecology and fungal biology in determining fungal biodiversity at different spatial scales.
In this Review, McDonaldet al. describe the mechanisms and outcomes of reassortment for three well-studied viral families — Cystoviridae, Orthomyxoviridae and Reoviridae— and discuss how these findings provide new perspectives on the replication and evolution of segmented RNA viruses.
In this Opinion article, Kreft and colleagues discuss how the combination of individual-based observations with individual-based models (IBMs) can lead to the new approach of microbial individual-based ecology (μIBE). They illustrate this point by describing how IBMs help to explore competitive and cooperative microbial interactions, which include the emergence of spatial patterns in biofilms and bacteria–phage dynamics.
