Vaccines are among the most useful and cost-effective tools for reducing the morbidity and mortality associated with infectious diseases. This special Focus issue highlights some of the latest progress in vaccine development and the pitfalls that have been encountered along the way.
The topics covered range from advances in our understanding of the immune response that will help in the development of new adjuvants and anti-bacterial vaccines, to the latest work on the development of a dengue virus vaccine. The accompanying library collects the most relevant recent publications from Nature Publishing Group.
Foreword
Vaccine renaissance
Jeffrey W. Almond
doi:10.1038/nrmicro1702
Nature Reviews Microbiology 5, 478-481 (2007)
News and Analysis
Vaccine Watch
Mapping the future of HIV vaccines
Gary J. Nabel
doi:10.1038/nrmicro1713
Nature Reviews Microbiology 5, 482-484 (2007)
Vaccine Watch
Tuberculosis vaccines — an update
Peter Andersen
doi:10.1038/nrmicro1703
Nature Reviews Microbiology 5, 484-487 (2007)
Vaccine Watch
Malaria vaccines: the stage we are at
Stephen M. Todryk & Adrian V. S. Hill
doi:10.1038/nrmicro1712
Nature Reviews Microbiology 5, 487-489 (2007)
Reviews
The contribution of immunology to the rational design of novel antibacterial vaccines
Stefan H.E. Kaufmann
doi:10.1038/nrmicro1688
Nature Reviews Microbiology 5, 491-504 (2007)
The perfect mix: recent progress in adjuvant research
Bruno Guy
doi:10.1038/nrmicro1681
Nature Reviews Microbiology 5, 505-517 (2007)
Prospects for a dengue virus vaccine
Stephen S. Whitehead, Joseph E. Blaney, Anna P. Durbin & Brian R. Murphy
doi:10.1038/nrmicro1690
Nature Reviews Microbiology 5, 518-528 (2007)
Rotavirus vaccines: recent developments and future considerations
Juana Angel, Manuel A. Franco & Harry B. Greenberg
doi:10.1038/nrmicro1692
Nature Reviews Microbiology 5, 529-539 (2007)
Clinical trials of Shigella vaccines: two steps forward and one step back on a long, hard road
Myron M. Levine, Karen L. Kotloff, Eileen M. Barry, Marcela F. Pasetti & Marcelo B. Sztein
doi:10.1038/nrmicro1662
Nature Reviews Microbiology 5, 540-553 (2007)
Perspective
Pathogenic epitopes, heterologous immunity and vaccine design
Raymond M. Welsh & Robert S. Fujinami
doi:10.1038/nrmicro1709
Nature Reviews Microbiology 5, 555-563 (2007)
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