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In this study, Liu et al. explore the interplay between a fungal effector and a plant cysteine protease and design a small-molecule compound aimed at targeting this effector to combat rice blast disease.
This study shows that hyphae formation is critical for Candida albicans gut colonization in the presence of commensal bacteria owing to the production of a hyphal-associated factor.
In this study, Armani-Tourret et al. show that the combination of panobinostat and pegylated interferon-α2a transforms the structure and composition of the HIV-1 reservoir and could potentially counter it.
In this Journal Club, Salvador Almagro-Moreno discusses a study by Kirn et al., which explores the emergence of virulence traits in Vibrio cholerae and demonstrates how the ability of this pathogen to colonize the host shares a common mechanism to its capacity to thrive in natural environments.
Wastewater genomic surveillance can transform global viral disease monitoring. This Genome Watch article explores the techniques, analytical pipelines and implications for public health.
In this Review, Tan and colleagues highlight recent efforts to discover non-traditional antimicrobials and explore the therapeutic potential of antimicrobial peptides and macrocycles, antibodies, bacteriophages and antisense-based therapeutics, focusing on how current research efforts are pushing these technologies towards clinical implementation.
Beneficial biofilms are in demand for diverse applications ranging from the production of specialized compounds to roles in agriculture and bioremediation. In this Review, Gescher and colleagues provide an overview of the applications, challenges and future of beneficial biofilms.
In this study, Ratiner et al. examine the advantages, challenges and future perspectives of utilizing microbiome data in personalized medicine for optimal patient care.
In this Review, Jassey and Jackson explore the intricate relationship between viruses and the autophagic pathway, highlighting how viruses either exploit or manipulate the autophagy pathway to influence their replication and survival within host cells.
