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Stem cells have been identified and characterized in several mammalian tissues. In addition, pluripotent embryonic stem cells have been derived from pre-implantation embryos in both mice and humans. Whereas the recent advances in stem-cell research have the potential to revolutionize medicine, the critical scientific challenge remains to elucidate the fundamental cellular and molecular controls of stem cells. An understanding of the molecular mechanisms that govern stem-cell fate and the identification of specific stem-cell markers is of fundamental significance in cell and developmental biology.
This Poster provides an overview of distinct embryonic and adult stem-cell types and the stem-cell markers that have been used to identify stem cells and cancer-stem-cell-enriched populations. The Poster is freely available thanks to support from Abcam.
