Poster

Targeting lipid signalling in disease

Matthias P. Wymann, Thomas R�ckle, Christian Rommel, Matthias Schwarz and Roger Schneiter

Lipids are important mediators in cancer and inflammation, and in cardiovascular, neurodegenerative and metabolic diseases. A complex protein�lipid signalling network that comprises phosphoinositides, sphingolipids, steroids and other lipid-derived mediators has been uncovered in recent years.

This Poster provides an overview of the protein�lipid signalling network and how this network can be exploited to attenuate proliferative, inflammatory and metabolic diseases, and accompanies a review article by Matthias P. Wymann and Roger Schneiter in the February 2008 issue, which contains a Focus on Lipids.

The Poster is freely available thanks to support from Merck Serono International S.A.

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    • Deadline: Jan 31 2010
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    The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression....

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    This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is...

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