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Research Highlights
Nature Reviews Molecular Cell Biology 9, 422 (1 June 2008) | doi:10.1038/nrm2420
Cellular microbiology: Virus plays dead
Abstract
Vaccinia virus is a large, complex, enveloped DNA virus that belongs to the Poxviridae family of viruses, which includes variola, the causative agent of smallpox. The infectious mature virus (MV) form of vaccinia has been shown to bind to actin-containing finger-like protrusions (filopodia) of the host cell and enter the cell in a pH-dependent manner.
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