Figures and Tables

From the following article:

Spatial and temporal coordination of mitosis by Ran GTPase

Paul R. Clarke & Chuanmao Zhang

Nature Reviews Molecular Cell Biology 9, 464-477 (June 2008)

doi:10.1038/nrm2410

Figure 2 - Spatial and temporal coordination of mitosis by Ran GTPase

Figure 2

Disruption of the GTP–GDP cycle of Ran causes aberrant mitotic spindle assembly.

Figure 3 - Spatial and temporal coordination of mitosis by Ran GTPase

Figure 3

Generation of a gradient of RanGTP complexed to importin-beta from mitotic chromosomes.

Figure 4 - Spatial and temporal coordination of mitosis by Ran GTPase

Figure 4

Release of spindle assembly factors from inhibitory complexes by RanGTP during mitotic spindle assembly.

Figure 5 - Spatial and temporal coordination of mitosis by Ran GTPase

Figure 5

Regulation of multiprotein complexes by RanGTP during mitotic spindle assembly.

Figure 6 - Spatial and temporal coordination of mitosis by Ran GTPase

Figure 6

A simple model for the role of Ran in nuclear-envelope assembly.

Figure 7 - Spatial and temporal coordination of mitosis by Ran GTPase

Figure 7

Regulation of RanGTP generation during prometaphase and metaphase by phosphorylation.