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Nature Reviews Molecular Cell Biology 9, 94–95 (1 February 2008) | doi:10.1038/nrm2337

Cell polarity: Heads or tails?

Francesca Cesari

Chop the head and tail off a flatworm and a new head grows back where a head should be and a new tail grows back where a tail should be. So, what decides whether it's heads or tails? Two reports now answer this century-old question.