Perspectives
Nature Reviews Molecular Cell Biology 8, 502-507 (June 2007) | doi:10.1038/nrm2189
Article series: Stem cells
Opinion: Embryonic stem-cell culture as a tool for developmental cell biology
Shin-Ichi Nishikawa1, Lars Martin Jakt1 & Takumi Era1 About the authors
Abstract
The cell biology of the early processes of mammalian embryogenesis, such as germ-layer formation, has been technically challenging to study owing to the size and accessibility of mammalian embryos. Embryonic stem cells, which can generate the three germ layers in vitro, are useful for studying embryogenesis at the cellular level. So, how can the study of embryonic stem cells and their differentiation provide a deeper understanding of the cell biology of early development?
Author affiliations
- Shin-Ichi Nishikawa, Lars Martin Jakt and Takumi Era are at the Laboratory of Stem Cell Research, Center for Developmental Biology, Minatojima Minamimachi 2-2-3, Chuoku, Kobe, 650-0047 Japan.
Correspondence to: Shin-Ichi Nishikawa1 Email: Nishikawa@cdb.riken.jp
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