Perspectives

Nature Reviews Molecular Cell Biology 7, 612-616 (August 2006) | doi:10.1038/nrm1946

OpinionNon-coding-RNA regulators of RNA polymerase II transcription

James A. Goodrich1 & Jennifer F. Kugel1  About the authors

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Several non-coding RNAs (ncRNAs) that regulate eukaryotic mRNA transcription have recently been discovered. Their mechanisms of action and biological roles are extremely diverse, which indicates that, so far, we have only had a glimpse of this new class of regulatory factor. Many surprises are likely to be revealed as further ncRNA transcriptional regulators are identified and characterized.

Author affiliations

  1. James A. Goodrich and Jennifer F. Kugel are in the Department of Chemistry and Biochemistry, University of Colorado at Boulder, 215 UCB, Boulder, Colorado 80309-0215, USA.
    Email: james.goodrich@colorado.edu; Email: jennifer.kugel@colorado.edu

Published online 24 May 2006

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