Figures and Tables

From the following article:

New insights into cystic fibrosis: molecular switches that regulate CFTR

William B. Guggino & Bruce A. Stanton

Nature Reviews Molecular Cell Biology 7, 426-436 (June 2006)

doi:10.1038/nrm1949

Figure 1 - New insights into cystic fibrosis: molecular switches that regulate CFTR

Figure 1

Molecular switches that regulate CFTR activity in the plasma membrane.

Figure 2 - New insights into cystic fibrosis: molecular switches that regulate CFTR

Figure 2

Regulation of CFTR activity in the plasma membrane of epithelial cells.

Figure 3 - New insights into cystic fibrosis: molecular switches that regulate CFTR

Figure 3

Model describing how molecular switches regulate CFTR trafficking.

Figure 4 - New insights into cystic fibrosis: molecular switches that regulate CFTR

Figure 4

Rab GTPases regulate CFTR trafficking, and thereby the localization of CFTR in the plasma membrane.

Figure 5 - New insights into cystic fibrosis: molecular switches that regulate CFTR

Figure 5

NHERF1 mediates the protein–protein interaction between CFTR and ENaC and facilitates reciprocal regulation between these channels.