Review
Nature Reviews Molecular Cell Biology 7, 404-414 (June 2006) | doi:10.1038/nrm1940
Harnessing actin dynamics for clathrin-mediated endocytosis
Marko Kaksonen1, Christopher P. Toret1 & David G. Drubin1 About the authors
Abstract
Actin polymerization often occurs at the plasma membrane to drive the protrusion of lamellipodia and filopodia at the leading edge of migrating cells. A role for actin polymerization in another cellular process that involves the reshaping of the plasma membrane — namely endocytosis — has recently been established. Live-cell imaging studies are shedding light on the order and timing of the molecular events and mechanisms of actin function during endocytosis.
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Author affiliations
- Department of Molecular and Cell Biology, University of California, Berkeley, California 94720-3202, USA.
Correspondence to: David G. Drubin1 Email: drubin@socrates.berkeley.edu
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