Review
Nature Reviews Molecular Cell Biology 7, 253-264 (April 2006) | doi:10.1038/nrm1891
NDR kinases regulate essential cell processes from yeast to humans
Alexander Hergovich1, Mario R. Stegert1, Debora Schmitz1 & Brian A. Hemmings1 About the authors
Abstract
Members of the NDR (nuclear Dbf2-related) protein-kinase family are essential components of pathways that control important cellular processes, such as morphological changes, mitotic exit, cytokinesis, cell proliferation and apoptosis. Recent progress has shed light on the mechanisms that underlie the regulation and function of the NDR family members. Combined data from yeast, worms, flies, mice and human cells now highlight the conserved and important roles of the different NDR kinases in distinct cellular processes.
- View At a Glance
Author affiliations
- Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, CH-4058 Basel, Switzerland.
Correspondence to: Brian A. Hemmings1 Email: brian.hemmings@fmi.ch
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Of Fat flies and Hippos, or the magic of animal sizeNature Structural & Molecular Biology News and Views (01 Dec 2006)
Hippo and its mission for growth controlNature Cell Biology News and Views (01 Oct 2003)
See all 3 matches for News And ViewsRESEARCH
Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in DrosophilaThe EMBO Journal Article (04 Apr 2007)
See all 11 matches for Research
