Table of contents


From The Editors

p1 | doi:10.1038/nrm1839

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Research Highlights

DNA replication: Turning back the genomic clock

p2 | doi:10.1038/nrm1843

Cancer: Taming Puma

p3 | doi:10.1038/nrm1844

In brief

RNA localization | DNA replication | Telomeres | Mechanism of Disease

p3 | doi:10.1038/nrm1846

Transcription: Stimulating saga

p4 | doi:10.1038/nrm1842

Signalling: Pathway paradox

p4 | doi:10.1038/nrm1848

Systems biology: Spotting interactions

p5 | doi:10.1038/nrm1845

Chromosome biology: Cooperate to separate

p6 | doi:10.1038/nrm1841

In the news

Manipulating methylation

p6 | doi:10.1038/nrm1847

Signalling: Controlling the sugar rush

p6 | doi:10.1038/nrm1850

Structure Watch

Turning heads | Caught conducting

p7 | doi:10.1038/nrm1849

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Reviews

How proteins produce cellular membrane curvature

Joshua Zimmerberg & Michael M. Kozlov

p9 | doi:10.1038/nrm1784

ILK, PINCH and parvin: the tIPP of integrin signalling

Kyle R. Legate, Eloi Montañez, Oliver Kudlacek & Reinhard Füssler

p20 | doi:10.1038/nrm1789

Life of a clathrin coat: insights from clathrin and AP structures

Melissa A. Edeling, Corinne Smith & David Owen

p32 | doi:10.1038/nrm1786

Developmental cell biology: Making digit patterns in the vertebrate limb

Cheryll Tickle

p45 | doi:10.1038/nrm1830

Function and regulation of Rnd proteins

Pierre Chardin

p54 | doi:10.1038/nrm1788

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Perspectives

Timeline

Clathrin-mediated endocytosis before fluorescent proteins

Michael G. Roth

p63 | doi:10.1038/nrm1783

Opinion

Protein linguistics — a grammar for modular protein assembly?

Mario Gimona

p68 | doi:10.1038/nrm1785

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