Perspectives
Nature Reviews Molecular Cell Biology 7, 63-68 (January 2006) | doi:10.1038/nrm1783
Timeline: Clathrin-mediated endocytosis before fluorescent proteins
Michael G. Roth1 About the author
Abstract
The recent technological advance of using fluorescent proteins to image endocytic protein traffic has resulted in a greater understanding of this dynamic process. However, most of the main concepts for how clathrin-mediated endocytosis functions were formulated long before intrinsically fluorescent proteins were available. These important conceptual breakthroughs came from the clever interpretation of simple observations.
Author affiliations
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Michael G. Roth is at the Department of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9038, USA.
Email: michael.roth@utsouthwestern.edu
Published online 15 November 2005
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