Perspectives
Nature Reviews Molecular Cell Biology 6, 743-748 (September 2005) | doi:10.1038/nrm1712
Opinion: Two-way traffic: centrosomes and the cell cycle
Greenfield Sluder1 About the author
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Abstract
The well recognized activities of the mammalian centrosome — microtubule nucleation, duplication, and organization of the primary cilium — are under the control of the cell cycle. However, the centrosome is more than just a follower of the cell cycle; it can also be essential for the cell to transit G1 and enter S phase. How the centrosome influences G1 progression is a mystery.
Author affiliations
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Greenfield Sluder is at the Department of Cell Biology, University of Massachusetts Medical School, 377 Plantation Street, Worcester, Massachusetts 01605, USA.
Email: greenfield.sluder@umassmed.edu
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