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Review
Nature Reviews Molecular Cell Biology 6, 635–645 (1 August 2005) | doi:10.1038/nrm1703
Transcriptional regulation and transformation by Myc proteins
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Abstract
Myc genes are key regulators of cell proliferation, and their deregulation contributes to the genesis of most human tumours. Recently, a wealth of data has shed new light on the biochemical functions of Myc proteins and on the mechanisms through which they function in cellular transformation.
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