Review
Nature Reviews Molecular Cell Biology 6, 635-645 (August 2005) | doi:10.1038/nrm1703
Transcriptional regulation and transformation by Myc proteins
Sovana Adhikary1 & Martin Eilers1 About the authors
Abstract
Myc genes are key regulators of cell proliferation, and their deregulation contributes to the genesis of most human tumours. Recently, a wealth of data has shed new light on the biochemical functions of Myc proteins and on the mechanisms through which they function in cellular transformation.
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Author affiliations
- Institute for Molecular Biology and Tumour Research, University of Marburg, Emil-Mannkopff-Strasse 2, 35033 Marburg, Germany.
Correspondence to: Martin Eilers1 Email: eilers@odin.imt.uni-marburg.de
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