Review

Nature Reviews Molecular Cell Biology 6, 635-645 (August 2005) | doi:10.1038/nrm1703

Transcriptional regulation and transformation by Myc proteins

Sovana Adhikary1 & Martin Eilers1  About the authors

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Myc genes are key regulators of cell proliferation, and their deregulation contributes to the genesis of most human tumours. Recently, a wealth of data has shed new light on the biochemical functions of Myc proteins and on the mechanisms through which they function in cellular transformation.

Author affiliations

  1. Institute for Molecular Biology and Tumour Research, University of Marburg, Emil-Mannkopff-Strasse 2, 35033 Marburg, Germany.

Correspondence to: Martin Eilers1 Email: eilers@odin.imt.uni-marburg.de

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