Review
Nature Reviews Molecular Cell Biology 6, 954-964 (December 2005) | doi:10.1038/nrm1765
Arp2/3 and SCAR: plants move to the fore
Michael J. Deeks1 & Patrick J. Hussey1 About the authors
Abstract
The actin-nucleating Arp2/3 complex is essential for life in yeast and animals, but not in plants, in which mutants of Arp2/3 complex components show relatively minor developmental abnormalities. Animal cells control the activity of the Arp2/3 complex through the suppressor of cyclic AMP receptor (SCAR) complex to achieve cell motility. Amazingly, plants have also retained the SCAR cell-motility pathway, and now provide a unique model for the study of new aspects of SCAR function in the absence of cell motility.
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Author affiliations
- The Integrative Cell Biology Laboratory, School of Biological and Biomedical Sciences, University of Durham, South Road, Durham, DH1 3LE, UK.
Correspondence to: Patrick J. Hussey1 Email: p.j.hussey@durham.ac.uk
Published online 15 November 2005
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