Perspectives
Nature Reviews Molecular Cell Biology 6, 885-890 (November 2005) | doi:10.1038/nrm1741
Innovation: Photoactivatable fluorescent proteins
Konstantin A. Lukyanov1, Dmitry M. Chudakov1, Sergey Lukyanov1 & Vladislav V. Verkhusha2 About the authors
Abstract
The fluorescence characteristics of photoactivatable proteins can be controlled by irradiating them with light of a specific wavelength, intensity and duration. This provides unique possibilities for the optical labelling and tracking of living cells, organelles and intracellular molecules in a spatio-temporal manner. Here, we discuss the properties of the available photoactivatable fluorescent proteins and their potential applications.
Author affiliations
- Konstantin A. Lukyanov, Dmitry M. Chudakov and Sergey Lukyanov are at the Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, Moscow 117997, Russia.
- Vladislav V. Verkhusha is at the Department of Pharmacology, University of Colorado at Denver and Health Sciences Center, Aurora, Colorado 80045, USA.
Correspondence to: Konstantin A. Lukyanov1 Email: kluk@ibch.ru
Correspondence to: Vladislav V. Verkhusha2 Email: vladislav.verkhusha@uchsc.edu
Published online 15 September 2005
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