Table of contents


In This Issue

p1 | doi:10.1038/nrm1579

Top

Research Highlights

Signalling: Fill in the blanks...

p2 | doi:10.1038/nrm1565

In brief

Protein evolution | Cell fate | Chromatin | Ageing

p3 | doi:10.1038/nrm1576

Cytoskeleton: Keeping dynamic

p3 | doi:10.1038/nrm1578

Nuclear transport: Details of the doorway

p4 | doi:10.1038/nrm1563

Cell cycle: What goes around...

p4 | doi:10.1038/nrm1574

Transcription: Nuclear actin muscles in

p5 | doi:10.1038/nrm1564

Cell cycle: Simply effective

p6 | doi:10.1038/nrm1561

Signalling: The stretch effect

p6 | doi:10.1038/nrm1562

Technique: Monitoring modification

p7 | doi:10.1038/nrm1566

Lipid metabolism: A two-step affair

p8 | doi:10.1038/nrm1575

In the news

Chromosomes 'worn down' by stress

p8 | doi:10.1038/nrm1577

Top

Reviews

Function and regulation of cullin–RING ubiquitin ligases

Matthew D. Petroski & Raymond J. Deshaies

p9 | doi:10.1038/nrm1547

The nuclear lamina comes of age

Yosef Gruenbaum, Ayelet Margalit, Robert D. Goldman, Dale K. Shumaker & Katherine L. Wilson

p21 | doi:10.1038/nrm1550

ADAMs: key components in EGFR signalling and development

Carl P. Blobel

p32 | doi:10.1038/nrm1548

p53: traffic cop at the crossroads of DNA repair and recombination

Sagar Sengupta & Curtis C. Harris

p44 | doi:10.1038/nrm1546

Focal adhesion kinase: in command and control of cell motility

Satyajit K. Mitra, Daniel A. Hanson & David D. Schlaepfer

p56 | doi:10.1038/nrm1549

RNA polymerases I and III, growth control and cancer

Robert J. White

p69 | doi:10.1038/nrm1551

Top

Perspective

Timeline

Proteolysis: from the lysosome to ubiquitin and the proteasome

Aaron Ciechanover

p79 | doi:10.1038/nrm1552

Natureview: Reviews and comment from the nature publishing group

p87 | doi:10.1038/nrm1580

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