Perspective
Nature Reviews Molecular Cell Biology 5, 763-769 (September 2004) | doi:10.1038/nrm1451
Innovation: Metabolite profiling: from diagnostics to systems biology
Alisdair R. Fernie1, Richard N. Trethewey2, Arno J. Krotzky2 & Lothar Willmitzer1 About the authors
Abstract
The concept of metabolite profiling has been around for several decades, but only recent technical innovations have allowed metabolite profiling to be carried out on a large scale — with respect to both the number of metabolites measured and the number of experiments carried out. As a result, the power of metabolite profiling as a technology platform for diagnostics, and the research areas of gene-function analysis and systems biology, is now beginning to be fully realized.
Author affiliations
- Alisdair R. Fernie and Lothar Willmitzer are at the Department of Molecular Physiology, Max-Planck-Institute for Molecular Plant Physiology, Am Mühlenberg 1, 14476 Golm, Germany.
- Richard N. Trethewey and Arno J. Krotzky are at metanomics GmbH and Co KGaA, and metanomics Health GmbH, Tegeler Weg 33, 10589 Berlin, Germany.
Correspondence to: Alisdair R. Fernie1 Email: fernie@mpimp-golm.mpg.de
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