Review
Nature Reviews Molecular Cell Biology 5, 635-646 (August 2004) | doi:10.1038/nrm1437
The co-workers of actin filaments: from cell structures to signals
Céline Revenu1, Rafika Athman1, Sylvie Robine1 & Daniel Louvard1 About the authors
Abstract
Cells have various surface architectures, which allow them to carry out different specialized functions. Actin microfilaments that are associated with the plasma membrane are important for generating these cell-surface specializations, and also provide the driving force for remodelling cell morphology and triggering new cell behaviour when the environment is modified. This phenomenon is achieved through a tight coupling between cell structure and signal transduction, a process that is modulated by the regulation of actin-binding proteins.
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Author affiliations
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UMR144 Centre National de la Recherche Scientifique/Institut Curie, Paris, France.
Email: daniel.louvard@curie.fr
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