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Review

Nature Reviews Molecular Cell Biology 5, 566–576 (1 July 2004) | doi:10.1038/nrm1424

Calcium, kinases and nodulation signalling in legumes

Giles E. D. Oldroyd & J. Allan Downie

Several genes have recently been identified using legume mutants that are defective for nodulation signalling. The proteins they encode include novel types of receptor-like kinase that are predicted to recognize bacterial nodulation (Nod) factors, a leucine-rich-repeat receptor kinase, a putative ion channel and a predicted Ca2+/calmodulin-dependent protein kinase. The identification of these gene products provides new insights into the legume signalling responses to rhizobial signals.