Perspectives
Nature Reviews Molecular Cell Biology 5, 582-588 (July 2004) | doi:10.1038/nrm1428
Innovation: Oligosaccharide microarrays to decipher the glyco code
Ten Feizi1 & Wengang Chai1 About the authors
Abstract
The oligosaccharide moieties of glycoproteins, glycolipids, proteoglycans and polysaccharides are highly diverse, the reason for this diversity is not yet understood. Neoglycolipid technology allows the generation of oligosaccharide probes with lipid tags from desired sources and is showing promise as a basis for oligosaccharide microarrays. Such microarrays would allow surveys of glycomes and proteomes to be carried out, which would enable the molecular definition of carbohydrate-recognition systems in whole organisms.
Author affiliations
- Ten Feizi and Wengang Chai are at The Glycosciences Laboratory, Imperial College London, Northwick Park Hospital Campus, Watford Road, Harrow, Middlesex HA1 3UJ, UK.
Correspondence to: Ten Feizi1 Email: t.feizi@imperial.ac.uk
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