Review

Nature Reviews Molecular Cell Biology 5, 983-997 (December 2004) | doi:10.1038/nrm1526

There is an Erratum (1 October 2005) associated with this article.

Meiosis: cell-cycle controls shuffle and deal

Adèle L. Marston1 & Angelika Amon1  About the authors

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Meiosis is the type of cell division that gives rise to eggs and sperm. Errors in the execution of this process can result in the generation of aneuploid gametes, which are associated with birth defects and infertility in humans. Here, we review recent findings on how cell-cycle controls ensure the coordination of meiotic events, with a particular focus on the segregation of chromosomes.

Author affiliations

  1. Center for Cancer Research, Howard Hughes Medical Institute, Massachusetts Institute of Technology, E17-233, 40 Ames Street, Cambridge, Massachusetts 02139, USA.

Correspondence to: Angelika Amon1 Email: angelika@mit.edu

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